Mouse issues

I am having issues with my mouse giving me lag when I use adobe photoshop 2014, the CPU goes above 30% or the HDD is doing large file movements. I have tried to update the drivers, i made sure that my motherboard bios are up to date. Any other ideas?

PC Specs:
Motherboard: ASUS SABERTOOTH 990FX R2.0
CPU: AMD FX-9590 Vishera 8-Core 4.7GHz
Ram: 2x Team Elite Plus 8GB 240-Pin DDR3 SDRAM DDR3 1333
Video Card: R7-250A-CLF4 Radeon R7 250 2GB
Power supply: EVGA 600 B 80 PLUS BRONZE
Storage: Seagate Barracuda 7200.14 ST3000DM001 3TB 7200 RPM 64MB Cache